Comparison of Protein and Peptide Targeting for the Development of a CD169-Based Vaccination Strategy Against Melanoma

Comparison of Protein and Peptide Targeting for the Development of a CD169-Based Vaccination Strategy Against Melanoma

CD169+ macrophages are part of the innate immune system and capture pathogens that enter secondary lymphoid organs such as the spleen and the lymph nodes. Their strategic location in the marginal zone of the spleen and the subcapsular sinus in the lymph node enables them to capture antigens from the...

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Bibliographic Details
Main Authors: Dieke van Dinther, Henrike Veninga, Mirjam Revet, Leoni Hoogterp, Katarzyna Olesek, Joanna Grabowska, Ellen G. F. Borg, Hakan Kalay, Yvette van Kooyk, Joke M. M. den Haan
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Immunology
Subjects:
CD169
Siglec-1
sialoadhesin
tumor immunology
macrophage
T cell
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01997/full

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