A Muscarinic Antagonist Reduces Airway Inflammation and Bronchoconstriction Induced by Ambient Particulate Matter in a Mouse Model of Asthma
Ambient particulate matter (PM) can increase airway inflammation and induce bronchoconstriction in asthma. This study aimed to investigate the effect of tiotropium bromide, a long-acting muscarinic antagonist, on airway inflammation and bronchoconstriction induced by ambient PM in a mouse model of a...
Main Authors: | Jun Kurai, Masanari Watanabe, Hiroyuki Sano, Kyoko Iwata, Degejirihu Hantan, Eiji Shimizu |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-06-01
|
Series: | International Journal of Environmental Research and Public Health |
Subjects: | |
Online Access: | http://www.mdpi.com/1660-4601/15/6/1189 |
Similar Items
-
The Effect of Seasonal Variations in Airborne Particulate Matter on Asthma-Related Airway Inflammation in Mice
by: Jun Kurai, et al.
Published: (2016-06-01) -
Development of a Pharmacological Screen for M5 Muscarinic Antagonists
by: Klein, Amanda Crystal
Published: (2011) -
The Impact of Muscarinic Receptor Antagonists on Airway Inflammation: A Systematic Review
by: Calzetta L, et al.
Published: (2021-02-01) -
Association of Short-Term Exposure to Ambient Fine Particulate Matter with Skin Symptoms in Schoolchildren: A Panel Study in a Rural Area of Western Japan
by: Masanari Watanabe, et al.
Published: (2017-03-01) -
Effect of aging on airway remodeling and muscarinic receptors in a murine acute asthma model
by: Kang JY, et al.
Published: (2013-10-01)