A Muscarinic Antagonist Reduces Airway Inflammation and Bronchoconstriction Induced by Ambient Particulate Matter in a Mouse Model of Asthma

A Muscarinic Antagonist Reduces Airway Inflammation and Bronchoconstriction Induced by Ambient Particulate Matter in a Mouse Model of Asthma

Ambient particulate matter (PM) can increase airway inflammation and induce bronchoconstriction in asthma. This study aimed to investigate the effect of tiotropium bromide, a long-acting muscarinic antagonist, on airway inflammation and bronchoconstriction induced by ambient PM in a mouse model of a...

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Bibliographic Details
Main Authors: Jun Kurai, Masanari Watanabe, Hiroyuki Sano, Kyoko Iwata, Degejirihu Hantan, Eiji Shimizu
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:International Journal of Environmental Research and Public Health
Subjects:
airway inflammation
asthma
muscarinic antagonists
ovalbumin mouse model
particulate matter
Online Access:http://www.mdpi.com/1660-4601/15/6/1189

Internet

http://www.mdpi.com/1660-4601/15/6/1189

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