Hypoxia changes the expression of the epidermal growth factor (EGF) system in human hearts and cultured cardiomyocytes.

Hypoxia changes the expression of the epidermal growth factor (EGF) system in human hearts and cultured cardiomyocytes.

<h4>Background</h4>The epidermal growth factor (EGF) receptors HER2 and HER4 and the ligands HB-EGF and NRG1 are crucial for heart development. The purpose of our study was to investigate the role of the complete EGF system in relation to hypoxia of the heart.<h4>Methodology/princi...

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Bibliographic Details
Main Authors: Mathias Munk, Ashfaque Ahmed Memon, Jens Peter Goetze, Lars Bo Nielsen, Ebba Nexo, Boe Sandahl Sorensen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22792252/pdf/?tool=EBI

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