MrpH, a new class of metal-binding adhesin, requires zinc to mediate biofilm formation.
Proteus mirabilis, a Gram-negative uropathogen, is a major causative agent in catheter-associated urinary tract infections (CAUTI). Mannose-resistant Proteus-like fimbriae (MR/P) are crucially important for P. mirabilis infectivity and are required for biofilm formation and auto-aggregation, as well...
Main Authors: | Wangshu Jiang, Wimal Ubhayasekera, Michael C Breed, Allison N Norsworthy, Nina Serr, Harry L T Mobley, Melanie M Pearson, Stefan D Knight |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-08-01
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Series: | PLoS Pathogens |
Online Access: | https://doi.org/10.1371/journal.ppat.1008707 |
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