Downregulation of Enhancer of Zeste Homolog 2 (EZH2) is essential for the Induction of Autophagy and Apoptosis in Colorectal Cancer Cells

Downregulation of Enhancer of Zeste Homolog 2 (EZH2) is essential for the Induction of Autophagy and Apoptosis in Colorectal Cancer Cells

Increasing evidence indicates that elevated expression of enhancer of zeste homolog 2 gene (EZH2) in many human malignant tumors acts a significant role in the oncogenic process. However, the underlying molecular mechanism is still unclarified. It is evident that apoptosis and autophagy of tumor ce...

Full description

Bibliographic Details
Main Authors: Yizhou Yao, Hao Hu, Yong Yang, Guoqiang Zhou, Zengfu Shang, Xiaodong Yang, Kang Sun, Shenghua Zhan, Zhengyuan Yu, Peiyao Li, Guofeng Pan, Liang Sun, Xinguo Zhu, Songbing He
Format: Article
Language:English
Published: MDPI AG 2016-10-01
Series:Genes
Subjects:
EZH2
 shRNA
 DZNep
 autophagy
 apoptosis
 colorectal cancer
Online Access:http://www.mdpi.com/2073-4425/7/10/83

Internet

http://www.mdpi.com/2073-4425/7/10/83

Similar Items