A novel B- and helper T-cell epitopes-based prophylactic vaccine against Echinococcus granulosus

A novel B- and helper T-cell epitopes-based prophylactic vaccine against Echinococcus granulosus

Introduction: In this study, we targeted the worm stage of Echinococcus granulosus to design a novel multi-epitope B- and helper T-cell based vaccine construct for immunization of dogs against this multi-host parasite. Methods: The vaccine was designed based on the local Eg14-3-3 antigen (Ag). DNA s...

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Bibliographic Details
Main Authors: Mohammad Mostafa Pourseif, Gholamali Moghaddam, Hossein Daghighkia, Ahmad Nematollahi, Yadollah Omidi
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2018-01-01
Series:BioImpacts
Subjects:
echinococcus granulosus
vaccine
eg14-3-3 antigen
t-helper epitope
leukocyte antigen
b-cell epitope
Online Access:https://bi.tbzmed.ac.ir/PDF/bi-8-39.pdf

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