Oral Toxicity of Okadaic Acid in Mice: Study of Lethality, Organ Damage, Distribution and Effects on Detoxifying Gene Expression
In vivo, after administration by gavage to mice and rats, okadaic acid has been reported to produce lesions in liver, small intestine and forestomach. Because several reports differ in the damage detected in different organs, and on okadaic acid distribution after consumption, we determined the toxi...
Main Authors: | Luis M. Botana, Félix V. Vega, Mercedes R. Vieytes, Paz Otero, José Manuel Cifuentes, Roberto Bermúdez, Amparo Alfonso, Henar López-Alonso, Andres C. Vieira, Juan A. Rubiolo |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2013-11-01
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Series: | Toxins |
Subjects: | |
Online Access: | http://www.mdpi.com/2072-6651/5/11/2093 |
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