Cervical cancer prevention in settings of high HIV prevalence
Despite being a preventable disease, cervical cancer is still the second most common cancer in women worldwide. HIV infection is associated with a higher incidence, more rapid progression, and increased recurrence rates of human papillomavirus (HPV)-associated cervical intra-epithelial neoplasia and...
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Format: | Article |
Language: | English |
Published: |
AOSIS
2011-05-01
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Series: | Southern African Journal of HIV Medicine |
Online Access: | https://sajhivmed.org.za/index.php/hivmed/article/view/192 |
Summary: | Despite being a preventable disease, cervical cancer is still the second most common cancer in women worldwide. HIV infection is associated with a higher incidence, more rapid progression, and increased recurrence rates of human papillomavirus (HPV)-associated cervical intra-epithelial neoplasia and invasive cancer. The disease burden in developing countries is the result of inadequate national health care infrastructures that cannot establish or sustain comprehensive screening programmes, together with a high prevalence of HIV infection, particularly in southern Africa. In this article, clinically relevant issues for primary prevention of cervical lesions by a quadrivalent HPV vaccine and the ‘screen-and-treat’ protocol in settings of high HIV prevalence will be explored. |
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ISSN: | 1608-9693 2078-6751 |