Multinodular and vacuolating neuronal tumor (MVNT): A presumably incidental and asymptomatic case in an intractable epilepsy patient
Introduction: Multinodular and vacuolating neuronal tumor (MVNT) had been initially described as an epilepsy-related brain tumor, but recent studies demonstrated it could be found incidentally in non-epilepsy patients. Case report: A 33-year-old woman with intractable post-encephalitis epilepsy pres...
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doaj-fd3e35f7252e4966b16998c58ba9d8ad2020-11-25T01:26:04ZengElsevierClinical Neurophysiology Practice2467-981X2019-01-014164167Multinodular and vacuolating neuronal tumor (MVNT): A presumably incidental and asymptomatic case in an intractable epilepsy patientSatoshi Kodama0Yuichiro Shirota1Akifumi Hagiwara2Juuri Otsuka3Kazuya Sato4Yusuke Sugiyama5Harushi Mori6Masako Watanabe7Masashi Hamada8Tatsushi Toda9Department of Neurology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan; Corresponding author.Department of Neurology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, JapanDepartment of Radiology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, JapanDepartment of Neurology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, JapanDepartment of Neurology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, JapanDepartment of Neurology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, JapanDepartment of Radiology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, JapanShinjuku Neuro Clinic, 3-21-18 Hyakunincho, Shinjuku-ku, Tokyo 169-0073, JapanDepartment of Neurology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, JapanDepartment of Neurology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, JapanIntroduction: Multinodular and vacuolating neuronal tumor (MVNT) had been initially described as an epilepsy-related brain tumor, but recent studies demonstrated it could be found incidentally in non-epilepsy patients. Case report: A 33-year-old woman with intractable post-encephalitis epilepsy presented a cluster of multinodular T2 hyperintensity in the left temporal lobe, which was very similar to the characteristics of MVNT. Long-term video electroencephalogram demonstrated that the habitual seizures were originated from bilateral temporal area and the interictal epileptic discharges were seen multifocally, although the lesions with MVNT appearance were localized in the left temporal lobe. It was presumed that the epilepsy in this patient was due to encephalitis in the past, and the link between the lesions and the epilepsy in this patient seemed weak. Conclusion: Although MVNT had been considered as an epilepsy-related brain tumor, we suggest it is not necessarily preferable to perform surgical resection of MVNT even on patients with epilepsy, unless epileptic foci are highly related to MVNT. Keywords: Post-encephalitis epilepsy, Brain tumor, Long-term video electroencephalogram, Magnetic resonance imaging (MRI)http://www.sciencedirect.com/science/article/pii/S2467981X19300277 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Satoshi Kodama Yuichiro Shirota Akifumi Hagiwara Juuri Otsuka Kazuya Sato Yusuke Sugiyama Harushi Mori Masako Watanabe Masashi Hamada Tatsushi Toda |
spellingShingle |
Satoshi Kodama Yuichiro Shirota Akifumi Hagiwara Juuri Otsuka Kazuya Sato Yusuke Sugiyama Harushi Mori Masako Watanabe Masashi Hamada Tatsushi Toda Multinodular and vacuolating neuronal tumor (MVNT): A presumably incidental and asymptomatic case in an intractable epilepsy patient Clinical Neurophysiology Practice |
author_facet |
Satoshi Kodama Yuichiro Shirota Akifumi Hagiwara Juuri Otsuka Kazuya Sato Yusuke Sugiyama Harushi Mori Masako Watanabe Masashi Hamada Tatsushi Toda |
author_sort |
Satoshi Kodama |
title |
Multinodular and vacuolating neuronal tumor (MVNT): A presumably incidental and asymptomatic case in an intractable epilepsy patient |
title_short |
Multinodular and vacuolating neuronal tumor (MVNT): A presumably incidental and asymptomatic case in an intractable epilepsy patient |
title_full |
Multinodular and vacuolating neuronal tumor (MVNT): A presumably incidental and asymptomatic case in an intractable epilepsy patient |
title_fullStr |
Multinodular and vacuolating neuronal tumor (MVNT): A presumably incidental and asymptomatic case in an intractable epilepsy patient |
title_full_unstemmed |
Multinodular and vacuolating neuronal tumor (MVNT): A presumably incidental and asymptomatic case in an intractable epilepsy patient |
title_sort |
multinodular and vacuolating neuronal tumor (mvnt): a presumably incidental and asymptomatic case in an intractable epilepsy patient |
publisher |
Elsevier |
series |
Clinical Neurophysiology Practice |
issn |
2467-981X |
publishDate |
2019-01-01 |
description |
Introduction: Multinodular and vacuolating neuronal tumor (MVNT) had been initially described as an epilepsy-related brain tumor, but recent studies demonstrated it could be found incidentally in non-epilepsy patients. Case report: A 33-year-old woman with intractable post-encephalitis epilepsy presented a cluster of multinodular T2 hyperintensity in the left temporal lobe, which was very similar to the characteristics of MVNT. Long-term video electroencephalogram demonstrated that the habitual seizures were originated from bilateral temporal area and the interictal epileptic discharges were seen multifocally, although the lesions with MVNT appearance were localized in the left temporal lobe. It was presumed that the epilepsy in this patient was due to encephalitis in the past, and the link between the lesions and the epilepsy in this patient seemed weak. Conclusion: Although MVNT had been considered as an epilepsy-related brain tumor, we suggest it is not necessarily preferable to perform surgical resection of MVNT even on patients with epilepsy, unless epileptic foci are highly related to MVNT. Keywords: Post-encephalitis epilepsy, Brain tumor, Long-term video electroencephalogram, Magnetic resonance imaging (MRI) |
url |
http://www.sciencedirect.com/science/article/pii/S2467981X19300277 |
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