Tailored Functionalized Magnetic Nanoparticles to Target Breast Cancer Cells Including Cancer Stem-Like Cells

Tailored Functionalized Magnetic Nanoparticles to Target Breast Cancer Cells Including Cancer Stem-Like Cells

Nanotechnology-based approaches hold substantial potential to avoid chemoresistance and minimize side effects. In this work, we have used biocompatible iron oxide magnetic nanoparticles (MNPs) called MF66 and functionalized with the antineoplastic drug doxorubicin (DOX) against MDA-MB-231 cells. Ele...

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Bibliographic Details
Main Authors: Ana Lazaro-Carrillo, Macarena Calero, Antonio Aires, Aitziber L. Cortajarena, Bruno M. Simões, Alfonso Latorre, Álvaro Somoza, Robert B. Clarke, Rodolfo Miranda, Angeles Villanueva
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cancers
Subjects:
magnetic iron oxide nanoparticles
doxorubicin
mitotic catastrophe
senescence
apoptosis
cancer stem-like cells
Online Access:https://www.mdpi.com/2072-6694/12/6/1397

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