13C-Enrichment of Urinary Uric Acid after l-[Ring-2-13C]Histidine Dose in Adult Humans

We determined whether ring-2 carbon of histidine is folate-dependently transferred to carbons 8 (C8) and/or 2 (C2) in urinary uric acid in humans. Two adults collected each urine void for four days. Aliquots of urine for the first day were used for baseline values; then the subjects ingested 0.7 g (...

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Bibliographic Details
Main Authors: Tsunenobu Tamura, Joseph E. Baggott
Format: Article
Language:English
Published: MDPI AG 2015-01-01
Series:Nutrients
Subjects:
Online Access:http://www.mdpi.com/2072-6643/7/1/697