Effect of Paternal DNA Damage on Paternal DNA Degradation and Early Embryonic Development in Mouse Embryo: Supporting Evidence by GammaH2AX Expression

Effect of Paternal DNA Damage on Paternal DNA Degradation and Early Embryonic Development in Mouse Embryo: Supporting Evidence by GammaH2AX Expression

This study was investigated to test whether the zygote recognized the topoisomerase II beta (TOP2B) mediated DNA fragmentation in epididymal spermatozoa or the nuclease degradation in vas deferens spermatozoa by testing for the presence of gammaH2AX (γH2AX). The γH2AX is phosphorylation of histone p...

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Bibliographic Details
Main Authors: Chang Jin Kim, Kyung-Bon Lee
Format: Article
Language:English
Published: The Korean Society of Animal Reproduction and Biotechnology 2019-09-01
Series:Journal of Animal Reproduction and Biotechnology
Subjects:
dna degradation
dna fragmentation
dna licensing
dna replication
gammah2ax
Online Access:http://www.e-jarb.org/journal/view.html?uid=2483&vmd=Full

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http://www.e-jarb.org/journal/view.html?uid=2483&vmd=Full

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