Sensitivity Analysis of Ion Channel Conductance on Myocardial Electromechanical Delay: Computational Study

Sensitivity Analysis of Ion Channel Conductance on Myocardial Electromechanical Delay: Computational Study

It is well known that cardiac electromechanical delay (EMD) can cause dyssynchronous heart failure (DHF), a prominent cardiovascular disease (CVD). This work computationally assesses the conductance variation of every ion channel on the cardiac cell to give rise to EMD prolongation. The electrical a...

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Bibliographic Details
Main Authors:	Ali Ikhsanul Qauli, Aroli Marcellinus, Ki Moo Lim
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-08-01
Series:	Frontiers in Physiology
Subjects:	myocardial action potential action potential duration electromechanical delay cardiac arrhythmia computational simulation
Online Access:	https://www.frontiersin.org/articles/10.3389/fphys.2021.697693/full

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