A New Approach for the Diagnosis of Systemic and Oral Diseases Based on Salivary Biomolecules

Early diagnosis represents the target of contemporary medicine and has an important role in the prognosis and further treatment. Saliva is a biofluid that generated a high interest among researchers due to its multiple advantages over other body fluids. The multitude of components that can act as bi...

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Main Authors:	Alexandra Roi, Laura C. Rusu, Ciprian I. Roi, Ruxandra E. Luca, Simina Boia, Roxana I. Munteanu
Format:	Article
Language:	English
Published:	Hindawi Limited 2019-01-01
Series:	Disease Markers
Online Access:	http://dx.doi.org/10.1155/2019/8761860

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spelling	doaj-fd08e5e8c6ab4733ae8e340f21d692fd2020-11-24T21:16:05ZengHindawi LimitedDisease Markers0278-02401875-86302019-01-01201910.1155/2019/87618608761860A New Approach for the Diagnosis of Systemic and Oral Diseases Based on Salivary BiomoleculesAlexandra Roi0Laura C. Rusu1Ciprian I. Roi2Ruxandra E. Luca3Simina Boia4Roxana I. Munteanu5Department of Oral Pathology, “Victor Babes” University of Medicine and Pharmacy, Timisoara, 2 Eftimie Murgu Sq., 300041, RomaniaDepartment of Oral Pathology, “Victor Babes” University of Medicine and Pharmacy, Timisoara, 2 Eftimie Murgu Sq., 300041, RomaniaDepartment of Anaesthesiology and Oral Surgery, “Victor Babeș” University of Medicine and Pharmacy, Timisoara, 2 Eftimie Murgu Sq., 300041, RomaniaDepartment of Oral Rehabilitation and Dental Emergencies, “Victor Babeș” University of Medicine and Pharmacy, Timisoara, 2 Eftimie Murgu Sq., 300041, RomaniaDepartment of Periodontology, “Victor Babeș” University of Medicine and Pharmacy, Timisoara, 2 Eftimie Murgu Sq., 300041, RomaniaDepartment of Oral Rehabilitation and Dental Emergencies, “Victor Babeș” University of Medicine and Pharmacy, Timisoara, 2 Eftimie Murgu Sq., 300041, RomaniaEarly diagnosis represents the target of contemporary medicine and has an important role in the prognosis and further treatment. Saliva is a biofluid that generated a high interest among researchers due to its multiple advantages over other body fluids. The multitude of components that can act as biomarkers influenced the existing technologies to develop protocols that could allow saliva to become the new noninvasive diagnostic method. Saliva as a diagnostic tool can bring substantial addition to the diagnostic armamentarium, providing important information about oral and general health. The diagnostic applications of saliva extended and had a rapid evolution due to the advancement in salivaomics. The present review summarizes the latest researches in saliva-related studies and explores the information and correlations that saliva can offer regarding the systemic and oral diseases, highlighting its great potential of diagnosis. It is expected that in the future specific guidelines and results regarding the salivary diagnostics are to be available, together with high-sensitivity and specificity tests for multiple systemic and oral diseases.http://dx.doi.org/10.1155/2019/8761860
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Alexandra Roi Laura C. Rusu Ciprian I. Roi Ruxandra E. Luca Simina Boia Roxana I. Munteanu
spellingShingle	Alexandra Roi Laura C. Rusu Ciprian I. Roi Ruxandra E. Luca Simina Boia Roxana I. Munteanu A New Approach for the Diagnosis of Systemic and Oral Diseases Based on Salivary Biomolecules Disease Markers
author_facet	Alexandra Roi Laura C. Rusu Ciprian I. Roi Ruxandra E. Luca Simina Boia Roxana I. Munteanu
author_sort	Alexandra Roi
title	A New Approach for the Diagnosis of Systemic and Oral Diseases Based on Salivary Biomolecules
title_short	A New Approach for the Diagnosis of Systemic and Oral Diseases Based on Salivary Biomolecules
title_full	A New Approach for the Diagnosis of Systemic and Oral Diseases Based on Salivary Biomolecules
title_fullStr	A New Approach for the Diagnosis of Systemic and Oral Diseases Based on Salivary Biomolecules
title_full_unstemmed	A New Approach for the Diagnosis of Systemic and Oral Diseases Based on Salivary Biomolecules
title_sort	new approach for the diagnosis of systemic and oral diseases based on salivary biomolecules
publisher	Hindawi Limited
series	Disease Markers
issn	0278-0240 1875-8630
publishDate	2019-01-01
description	Early diagnosis represents the target of contemporary medicine and has an important role in the prognosis and further treatment. Saliva is a biofluid that generated a high interest among researchers due to its multiple advantages over other body fluids. The multitude of components that can act as biomarkers influenced the existing technologies to develop protocols that could allow saliva to become the new noninvasive diagnostic method. Saliva as a diagnostic tool can bring substantial addition to the diagnostic armamentarium, providing important information about oral and general health. The diagnostic applications of saliva extended and had a rapid evolution due to the advancement in salivaomics. The present review summarizes the latest researches in saliva-related studies and explores the information and correlations that saliva can offer regarding the systemic and oral diseases, highlighting its great potential of diagnosis. It is expected that in the future specific guidelines and results regarding the salivary diagnostics are to be available, together with high-sensitivity and specificity tests for multiple systemic and oral diseases.
url	http://dx.doi.org/10.1155/2019/8761860
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A New Approach for the Diagnosis of Systemic and Oral Diseases Based on Salivary Biomolecules

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