The COP9 signalosome, cullin 3 and Keap1 supercomplex regulates CHOP stability and adipogenesis

The COP9 signalosome, cullin 3 and Keap1 supercomplex regulates CHOP stability and adipogenesis

Summary Obesity is one of the most serious health problems of the 21st century. It is associated with highly increased risk of type 2 diabetes, high blood pressure, cardiovascular disease as well as several cancers. The expansion of the fat tissue needs the differentiation of preadipocytes to adipoc...

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Bibliographic Details
Main Authors: Xiaohua Huang, Jürgen Ordemann, Joachim M. Müller, Wolfgang Dubiel
Format: Article
Language:English
Published: The Company of Biologists 2012-06-01
Series:Biology Open
Subjects:
Adipogenesis
CHOP
COP9 signalosome
Cullin 3
Keap1
Online Access:http://bio.biologists.org/content/1/8/705

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