Pathway-centric analysis of the DNA damage response to chemotherapeutic agents in two breast cell lines

The response to DNA damage by alkylation and DNA topoisomerase inhibition was studied in two breast cancer cells lines. We present data from both a shotgun and a targeted, pathway-centric approach to highlight the different DNA repair pathway modulation in the cell lines and the correlation with via...

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Bibliographic Details
Main Authors: Linn Antberg, Paolo Cifani, Fredrik Levander, Peter James
Format: Article
Language:English
Published: Elsevier 2015-09-01
Series:EuPA Open Proteomics
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2212968515000148