Modeling mitigation of influenza epidemics by baloxavir

Modeling mitigation of influenza epidemics by baloxavir

Here, the authors implement a mathematical model that describes how Baloxavir antiviral-induced inhibition of influenza virus replication in infected individuals affects the spread of the virus during epidemics, suggesting that both the scaling up and acceleration of treatment would avert substantia...

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Main Authors: Zhanwei Du, Ciara Nugent, Alison P. Galvani, Robert M. Krug, Lauren Ancel Meyers
Format: Article
Language:English
Published: Nature Publishing Group 2020-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16585-y
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spelling doaj-fcf4d646137b4d9aa9dd957c0593cd7e2021-06-06T11:15:39ZengNature Publishing GroupNature Communications2041-17232020-06-011111610.1038/s41467-020-16585-yModeling mitigation of influenza epidemics by baloxavirZhanwei Du0Ciara Nugent1Alison P. Galvani2Robert M. Krug3Lauren Ancel Meyers4Department of Integrative Biology, University of Texas at AustinDepartment of Statistics and Data Science, University of Texas at AustinCenter for Infectious Disease Modeling and Analysis, Yale School of Public HealthDepartment of Molecular Biosciences, John Ring LaMontagne Center for Infectious Disease, Institute for Cellular and Molecular Biology, University of Texas at AustinDepartment of Integrative Biology, University of Texas at AustinHere, the authors implement a mathematical model that describes how Baloxavir antiviral-induced inhibition of influenza virus replication in infected individuals affects the spread of the virus during epidemics, suggesting that both the scaling up and acceleration of treatment would avert substantial influenza morbidity and mortality every year.https://doi.org/10.1038/s41467-020-16585-y
collection DOAJ
language English
format Article
sources DOAJ
author Zhanwei Du
Ciara Nugent
Alison P. Galvani
Robert M. Krug
Lauren Ancel Meyers
spellingShingle Zhanwei Du
Ciara Nugent
Alison P. Galvani
Robert M. Krug
Lauren Ancel Meyers
Modeling mitigation of influenza epidemics by baloxavir
Nature Communications
author_facet Zhanwei Du
Ciara Nugent
Alison P. Galvani
Robert M. Krug
Lauren Ancel Meyers
author_sort Zhanwei Du
title Modeling mitigation of influenza epidemics by baloxavir
title_short Modeling mitigation of influenza epidemics by baloxavir
title_full Modeling mitigation of influenza epidemics by baloxavir
title_fullStr Modeling mitigation of influenza epidemics by baloxavir
title_full_unstemmed Modeling mitigation of influenza epidemics by baloxavir
title_sort modeling mitigation of influenza epidemics by baloxavir
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2020-06-01
description Here, the authors implement a mathematical model that describes how Baloxavir antiviral-induced inhibition of influenza virus replication in infected individuals affects the spread of the virus during epidemics, suggesting that both the scaling up and acceleration of treatment would avert substantial influenza morbidity and mortality every year.
url https://doi.org/10.1038/s41467-020-16585-y
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AT alisonpgalvani modelingmitigationofinfluenzaepidemicsbybaloxavir
AT robertmkrug modelingmitigationofinfluenzaepidemicsbybaloxavir
AT laurenancelmeyers modelingmitigationofinfluenzaepidemicsbybaloxavir
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