New potential antiproliferative monophosphoester 2-aminoethyl dihydrogen phosphate in K-562 and K-562 MDR+ leukemia cells

New potential antiproliferative monophosphoester 2-aminoethyl dihydrogen phosphate in K-562 and K-562 MDR+ leukemia cells

The main obstacle in the treatment of cancer patients has been resistance to multiple drugs, leading to the need to develop molecules with a higher specificity target. The liposomal formulation DODAC/2-AEH2P has antitumor potential, inducing apoptosis in several tumor types. Human chronic myeloid le...

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Bibliographic Details
Main Authors: TO. Conceição, LGS. Cabral, MG. Laveli-Silva, JC. Pacheco, MG. Alves, DC. Rabelo, RAN. Laiso, DA. Maria
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Leukemia
Drug resistance
DODAC carrier
Liposomal formulation
2-AEH2P
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221008374

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http://www.sciencedirect.com/science/article/pii/S0753332221008374

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