Potential Preventive Strategies for Amyotrophic Lateral Sclerosis

Potential Preventive Strategies for Amyotrophic Lateral Sclerosis

It may seem useless to propose preventive measures for a disease without established pathogenesis and successful therapy, such as amyotrophic lateral sclerosis (ALS). However, we will show that ALS shares essential molecular mechanisms with aging and that established anti-aging strategies, such as h...

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Main Authors: B. Kuraszkiewicz, H. Goszczyńska, T. Podsiadły-Marczykowska, M. Piotrkiewicz, P. Andersen, M. Gromicho, J. Grosskreutz, M. Kuźma-Kozakiewicz, S. Petri, B. Stubbendorf, K. Szacka, H. Uysal, M. de Carvalho
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Neuroscience
Subjects:
amyotrophic lateral sclerosis
aging
dietary habits
exercise
gut microbiome
psychological stress
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00428/full
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spelling doaj-fce5a765972a449e887d3376e4e8d3f92020-11-25T03:27:01ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2020-05-011410.3389/fnins.2020.00428504282Potential Preventive Strategies for Amyotrophic Lateral SclerosisB. Kuraszkiewicz0H. Goszczyńska1T. Podsiadły-Marczykowska2M. Piotrkiewicz3P. Andersen4M. Gromicho5J. Grosskreutz6J. Grosskreutz7M. Kuźma-Kozakiewicz8S. Petri9B. Stubbendorf10K. Szacka11H. Uysal12M. de Carvalho13Department of Methods of Brain Imaging and Functional Research of Nervous System, Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Warsaw, PolandDepartment of Methods of Brain Imaging and Functional Research of Nervous System, Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Warsaw, PolandDepartment of Methods of Brain Imaging and Functional Research of Nervous System, Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Warsaw, PolandDepartment of Methods of Brain Imaging and Functional Research of Nervous System, Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Warsaw, PolandDepartment of Clinical Sciences, Umeå University, Umeå, SwedenInstitute of Physiology, Faculty of Medicine, University of Lisbon, Lisbon, PortugalDepartment of Neurology, University Hospital Jena, Jena, GermanyJena Centre for Healthy Aging, University Hospital Jena, Jena, GermanyDepartment of Neurology, Medical University of Warsaw, Warsaw, PolandClinic for Neurology, Hannover Medical School, Hanover, GermanyDepartment of Neurology, University Hospital Jena, Jena, GermanyDepartment of Neurology, Medical University of Warsaw, Warsaw, PolandAkdeniz University Faculty of Medicine, Antalya, TurkeyInstitute of Physiology, Faculty of Medicine, University of Lisbon, Lisbon, PortugalIt may seem useless to propose preventive measures for a disease without established pathogenesis and successful therapy, such as amyotrophic lateral sclerosis (ALS). However, we will show that ALS shares essential molecular mechanisms with aging and that established anti-aging strategies, such as healthy diet or individually adjusted exercise, may be successfully applied to ameliorate the condition of ALS patients. These strategies might be applied for prevention if persons at ALS risk could be identified early enough. Recent research advances indicate that this may happen soon.https://www.frontiersin.org/article/10.3389/fnins.2020.00428/fullamyotrophic lateral sclerosisagingdietary habitsexercisegut microbiomepsychological stress
collection DOAJ
language English
format Article
sources DOAJ
author B. Kuraszkiewicz
H. Goszczyńska
T. Podsiadły-Marczykowska
M. Piotrkiewicz
P. Andersen
M. Gromicho
J. Grosskreutz
J. Grosskreutz
M. Kuźma-Kozakiewicz
S. Petri
B. Stubbendorf
K. Szacka
H. Uysal
M. de Carvalho
spellingShingle B. Kuraszkiewicz
H. Goszczyńska
T. Podsiadły-Marczykowska
M. Piotrkiewicz
P. Andersen
M. Gromicho
J. Grosskreutz
J. Grosskreutz
M. Kuźma-Kozakiewicz
S. Petri
B. Stubbendorf
K. Szacka
H. Uysal
M. de Carvalho
Potential Preventive Strategies for Amyotrophic Lateral Sclerosis
Frontiers in Neuroscience
amyotrophic lateral sclerosis
aging
dietary habits
exercise
gut microbiome
psychological stress
author_facet B. Kuraszkiewicz
H. Goszczyńska
T. Podsiadły-Marczykowska
M. Piotrkiewicz
P. Andersen
M. Gromicho
J. Grosskreutz
J. Grosskreutz
M. Kuźma-Kozakiewicz
S. Petri
B. Stubbendorf
K. Szacka
H. Uysal
M. de Carvalho
author_sort B. Kuraszkiewicz
title Potential Preventive Strategies for Amyotrophic Lateral Sclerosis
title_short Potential Preventive Strategies for Amyotrophic Lateral Sclerosis
title_full Potential Preventive Strategies for Amyotrophic Lateral Sclerosis
title_fullStr Potential Preventive Strategies for Amyotrophic Lateral Sclerosis
title_full_unstemmed Potential Preventive Strategies for Amyotrophic Lateral Sclerosis
title_sort potential preventive strategies for amyotrophic lateral sclerosis
publisher Frontiers Media S.A.
series Frontiers in Neuroscience
issn 1662-453X
publishDate 2020-05-01
description It may seem useless to propose preventive measures for a disease without established pathogenesis and successful therapy, such as amyotrophic lateral sclerosis (ALS). However, we will show that ALS shares essential molecular mechanisms with aging and that established anti-aging strategies, such as healthy diet or individually adjusted exercise, may be successfully applied to ameliorate the condition of ALS patients. These strategies might be applied for prevention if persons at ALS risk could be identified early enough. Recent research advances indicate that this may happen soon.
topic amyotrophic lateral sclerosis
aging
dietary habits
exercise
gut microbiome
psychological stress
url https://www.frontiersin.org/article/10.3389/fnins.2020.00428/full
work_keys_str_mv AT bkuraszkiewicz potentialpreventivestrategiesforamyotrophiclateralsclerosis
AT hgoszczynska potentialpreventivestrategiesforamyotrophiclateralsclerosis
AT tpodsiadłymarczykowska potentialpreventivestrategiesforamyotrophiclateralsclerosis
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AT huysal potentialpreventivestrategiesforamyotrophiclateralsclerosis
AT mdecarvalho potentialpreventivestrategiesforamyotrophiclateralsclerosis
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