MicroRNA discovery by similarity search to a database of RNA-seq profiles

In silico generated search for microRNAs (miRNAs)has been driven by methods compiling structural featuresof the miRNA precursor hairpin, as well as tosome degree combining this with the analysis of RNA-seqprofiles for which the miRNA typically leave thedrosha/dicer fingerprint of 1–2 ∼22nt blocks of...

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Bibliographic Details
Main Authors: Sachin ePundhir, Jan eGorodkin
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-07-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00133/full