Neoadjuvant Sorafenib Treatment of Clear Cell Renal Cell Carcinoma and Release of Circulating Tumor Fragments

BACKGROUND: Clear cell renal cell carcinoma (ccRCC) is characterized by high constitutive vascular endothelial growth factor A (VEGF-A) production that induces a specific vascular phenotype. We previously reported that this phenotype may allow shedding of multicellular tumor fragments into the circ...

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Bibliographic Details
Main Authors: Gursah Kats-Ugurlu, Egbert Oosterwijk, Stijn Muselaers, Jeannette Oosterwijk-Wakka, Christina Hulsbergen-van de Kaa, Mirjam de Weijert, Han van Krieken, Ingrid Desar, Carla van Herpen, Cathy Maass, Rob de Waal, Peter Mulders, William Leenders
Format: Article
Language:English
Published: Elsevier 2014-03-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558614000189

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