Transforming RNA-Seq data to improve the performance of prognostic gene signatures.

Gene expression measurements have successfully been used for building prognostic signatures, i.e for identifying a short list of important genes that can predict patient outcome. Mostly microarray measurements have been considered, and there is little advice available for building multivariable risk...

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Bibliographic Details
Main Authors: Isabella Zwiener, Barbara Frisch, Harald Binder
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3885686?pdf=render