Identification of Bacterial Protein Interaction Partners Points to New Intracellular Functions of Francisella tularensis Glyceraldehyde-3-Phosphate Dehydrogenase

Identification of Bacterial Protein Interaction Partners Points to New Intracellular Functions of Francisella tularensis Glyceraldehyde-3-Phosphate Dehydrogenase

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is well known for its involvement in numerous non-metabolic processes inside mammalian cells. Alternative functions of prokaryotic GAPDH are mainly deduced from its extracellular localization ability to bind to selected host proteins. Data on its part...

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Bibliographic Details
Main Authors: Monika Kopeckova, Ivona Pavkova, Marek Link, Pavel Rehulka, Jiri Stulik
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Microbiology
Subjects:
protein–protein interaction
multifunctional enzyme
Francisella tularensis
glyceraldehyde-3-phosphate dehydrogenase
SILAC
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.576618/full

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