Improving Phylogeny Reconstruction at the Strain Level Using Peptidome Datasets.
Typical bacterial strain differentiation methods are often challenged by high genetic similarity between strains. To address this problem, we introduce a novel in silico peptide fingerprinting method based on conventional wet-lab protocols that enables the identification of potential strain-specific...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-12-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC5198984?pdf=render |