Human NK Cells Develop an Exhaustion Phenotype During Polar Degranulation at the Aspergillus fumigatus Hyphal Synapse

Human NK Cells Develop an Exhaustion Phenotype During Polar Degranulation at the Aspergillus fumigatus Hyphal Synapse

Pulmonary aspergillosis is an opportunistic fungal infection affecting immunocompromised individuals. Increasing understanding of natural killer (NK) cell immunobiology has aroused considerable interest around the role of NK cells in pulmonary aspergillosis in the immunocompromised host. Murine stud...

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Bibliographic Details
Main Authors: Virginia Santiago, Katayoun Rezvani, Takuya Sekine, Justin Stebbing, Peter Kelleher, Darius Armstrong-James
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Immunology
Subjects:
NK cells
Aspergillus fumigatus
fungal disease
immunocompromise
leukaemia
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02344/full

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