Copy number gain of pro-inflammatory genes in patients with HBV-related acute-on-chronic liver failure

Copy number gain of pro-inflammatory genes in patients with HBV-related acute-on-chronic liver failure

Abstract Background Host genetic factors such as single nucleotide variations may play a crucial role in the onset and progression of HBV-related acute-on-chronic liver failure (ACLF). However, the underlying genomic copy number variations (CNVs) involved in the pathology are currently unclear. Meth...

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Bibliographic Details
Main Authors: Fengming Sun, Wenting Tan, Yunjie Dan, Xiuhua Wang, Yanzhi Guo, Guohong Deng
Format: Article
Language:English
Published: BMC 2020-12-01
Series:BMC Medical Genomics
Subjects:
Copy number variations
HBV-related ACLF
GWAS
HBV-ACLF
Acute-on-chronic liver failure
Online Access:https://doi.org/10.1186/s12920-020-00835-5

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