Causes and Consequences of HPV Integration in Head and Neck Squamous Cell Carcinomas: State of the Art

Causes and Consequences of HPV Integration in Head and Neck Squamous Cell Carcinomas: State of the Art

A constantly increasing incidence in high-risk Human Papillomaviruses (HPV)s driven head and neck squamous cell carcinomas (HNSCC)s, especially of oropharyngeal origin, is being observed. During persistent infections, viral DNA integration into the host genome may occur. Studies are examining if the...

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Bibliographic Details
Main Authors: Harini Balaji, Imke Demers, Nora Wuerdemann, Julia Schrijnder, Bernd Kremer, Jens Peter Klussmann, Christian Ulrich Huebbers, Ernst-Jan Maria Speel
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
high-risk human papillomaviruses
head and neck squamous cell carcinomas
viral DNA integration
PCR
DIPS-PCR
APOT-PCR
Online Access:https://www.mdpi.com/2072-6694/13/16/4089

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