A Revised Point-to-Point Calibration Approach with Adaptive Errors Correction to Weaken Initial Sensitivity of Cuff-Less Blood Pressure Estimation

Initial calibration is a great challenge for cuff-less blood pressure (BP) measurement. The traditional one point-to-point (oPTP) calibration procedure only uses one sample/point to obtain unknown parameters of a specific model in a calm state. In fact, parameters such as pulse transit time (PTT) an...

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Main Authors: Jiang Shao, Ping Shi, Sijung Hu, Hongliu Yu
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Sensors
Subjects:
Online Access:https://www.mdpi.com/1424-8220/20/8/2205
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spelling doaj-fcacd7dc08a94640aace07a678db11c62020-11-25T02:27:05ZengMDPI AGSensors1424-82202020-04-01202205220510.3390/s20082205A Revised Point-to-Point Calibration Approach with Adaptive Errors Correction to Weaken Initial Sensitivity of Cuff-Less Blood Pressure EstimationJiang Shao0Ping Shi1Sijung Hu2Hongliu Yu3Institute of Rehabilitation Engineering and Technology, University of Shanghai for Science and Technology, Shanghai 200093, ChinaInstitute of Rehabilitation Engineering and Technology, University of Shanghai for Science and Technology, Shanghai 200093, ChinaWolfson School of Mechanical, Electrical and Manufacturing Engineering, Loughborough University, Loughborough, Leicestershire LE11 3TU, UKInstitute of Rehabilitation Engineering and Technology, University of Shanghai for Science and Technology, Shanghai 200093, ChinaInitial calibration is a great challenge for cuff-less blood pressure (BP) measurement. The traditional one point-to-point (oPTP) calibration procedure only uses one sample/point to obtain unknown parameters of a specific model in a calm state. In fact, parameters such as pulse transit time (PTT) and BP still have slight fluctuations at rest for each subject. The conventional oPTP method had a strong sensitivity in the selection of initial value. Yet, the initial sensitivity of calibration has not been reported and investigated in cuff-less BP motoring. In this study, a mean point-to-point (mPTP) paring calibration method through averaging and balancing calm or peaceful states was proposed for the first time. Thus, based on mPTP, a factor point-to-point (fPTP) paring calibration method through introducing the penalty factor was further proposed to improve and optimize the performance of BP estimation. Using the oPTP, mPTP, and fPTP methods, a total of more than 100,000 heartbeat samples from 21 healthy subjects were tested and validated in the PTT-based BP monitoring technologies. The results showed that the mPTP and fPTP methods significantly improved the performance of estimating BP compared to the conventional oPTP method. Moreover, the mPTP and fPTP methods could be widely popularized and applied, especially the fPTP method, on estimating cuff-less diastolic blood pressure (DBP). To this extent, the fPTP method weakens the initial calibration sensitivity of cuff-less BP estimation and fills in the ambiguity for individualized calibration procedure.https://www.mdpi.com/1424-8220/20/8/2205point-to-point pairing methodinitial sensitivitypenalty factorcorrecting errorscuff-less blood pressure
collection DOAJ
language English
format Article
sources DOAJ
author Jiang Shao
Ping Shi
Sijung Hu
Hongliu Yu
spellingShingle Jiang Shao
Ping Shi
Sijung Hu
Hongliu Yu
A Revised Point-to-Point Calibration Approach with Adaptive Errors Correction to Weaken Initial Sensitivity of Cuff-Less Blood Pressure Estimation
Sensors
point-to-point pairing method
initial sensitivity
penalty factor
correcting errors
cuff-less blood pressure
author_facet Jiang Shao
Ping Shi
Sijung Hu
Hongliu Yu
author_sort Jiang Shao
title A Revised Point-to-Point Calibration Approach with Adaptive Errors Correction to Weaken Initial Sensitivity of Cuff-Less Blood Pressure Estimation
title_short A Revised Point-to-Point Calibration Approach with Adaptive Errors Correction to Weaken Initial Sensitivity of Cuff-Less Blood Pressure Estimation
title_full A Revised Point-to-Point Calibration Approach with Adaptive Errors Correction to Weaken Initial Sensitivity of Cuff-Less Blood Pressure Estimation
title_fullStr A Revised Point-to-Point Calibration Approach with Adaptive Errors Correction to Weaken Initial Sensitivity of Cuff-Less Blood Pressure Estimation
title_full_unstemmed A Revised Point-to-Point Calibration Approach with Adaptive Errors Correction to Weaken Initial Sensitivity of Cuff-Less Blood Pressure Estimation
title_sort revised point-to-point calibration approach with adaptive errors correction to weaken initial sensitivity of cuff-less blood pressure estimation
publisher MDPI AG
series Sensors
issn 1424-8220
publishDate 2020-04-01
description Initial calibration is a great challenge for cuff-less blood pressure (BP) measurement. The traditional one point-to-point (oPTP) calibration procedure only uses one sample/point to obtain unknown parameters of a specific model in a calm state. In fact, parameters such as pulse transit time (PTT) and BP still have slight fluctuations at rest for each subject. The conventional oPTP method had a strong sensitivity in the selection of initial value. Yet, the initial sensitivity of calibration has not been reported and investigated in cuff-less BP motoring. In this study, a mean point-to-point (mPTP) paring calibration method through averaging and balancing calm or peaceful states was proposed for the first time. Thus, based on mPTP, a factor point-to-point (fPTP) paring calibration method through introducing the penalty factor was further proposed to improve and optimize the performance of BP estimation. Using the oPTP, mPTP, and fPTP methods, a total of more than 100,000 heartbeat samples from 21 healthy subjects were tested and validated in the PTT-based BP monitoring technologies. The results showed that the mPTP and fPTP methods significantly improved the performance of estimating BP compared to the conventional oPTP method. Moreover, the mPTP and fPTP methods could be widely popularized and applied, especially the fPTP method, on estimating cuff-less diastolic blood pressure (DBP). To this extent, the fPTP method weakens the initial calibration sensitivity of cuff-less BP estimation and fills in the ambiguity for individualized calibration procedure.
topic point-to-point pairing method
initial sensitivity
penalty factor
correcting errors
cuff-less blood pressure
url https://www.mdpi.com/1424-8220/20/8/2205
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