Tumor growth decreases NK and B cells as well as common lymphoid progenitor.

It is well established that chronic tumor growth results in functional inactivation of T cells and NK cells. It is less clear, however, whether lymphopoeisis is affected by tumor growth.In our efforts of analyzing the impact of tumor growth on NK cell development, we observed a major reduction of NK...

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Bibliographic Details
Main Authors: John Richards, Beth McNally, Xianfeng Fang, Michael A Caligiuri, Pan Zheng, Yang Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2527520?pdf=render