SARS-CoV-2 interacts with platelets and megakaryocytes via ACE2-independent mechanism

SARS-CoV-2 interacts with platelets and megakaryocytes via ACE2-independent mechanism

Abstract Evidence suggests that platelets may directly interact with SARS-CoV-2, raising the concern whether ACE2 receptor plays a role in this interaction. The current study showed that SARS-CoV-2 interacts with both platelets and megakaryocytes despite the limited efficiency. Abundance of the conv...

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Bibliographic Details
Main Authors: Shu Shen, Jingyuan Zhang, Yaohui Fang, Sihong Lu, Jun Wu, Xin Zheng, Fei Deng
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Journal of Hematology & Oncology
Subjects:
COVID-19
SARS-CoV-2
Platelets
Platelet activation
ACE2
Alternative receptors
Online Access:https://doi.org/10.1186/s13045-021-01082-6

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