Beta-amyloid impairs reelin signaling.
Reelin is a signaling protein increasingly associated with the pathogenesis of Alzheimer's disease that relevantly modulates tau phosphorylation. We have previously demonstrated that β-amyloid peptide (Aβ) alters reelin expression. We have now attempted to determine whether abnormal reelin trig...
Main Authors: | Inmaculada Cuchillo-Ibáñez, Valeria Balmaceda, Arancha Botella-López, Alberto Rabano, Jesus Avila, Javier Sáez-Valero |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3741172?pdf=render |
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