DETECTION OF ANTI-HBC AND ANTI-HBS ANTIBODIES IN BLOOD DONORS NEGATIVE

The Objectives: safety of blood products is one of the major issues in the area of transfusion medicine. In previous study we found that hepatitis B virus was epidemic in some of Basrah medical institutions to assess the prevalence of anti-HBc and anti-HBs antibodies in serum samples of healthy bloo...

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Bibliographic Details
Main Authors: Maha M. Hameed, Hayder A. Al-Hmudi, Saad S.Hamadi
Format: Article
Language:English
Published: University of Basrah 2012-06-01
Series:The Medical Journal of Basrah University
Subjects:
Online Access:https://mjbu.uobasrah.edu.iq/article_64011_21dd8a4ed52e38645154217804f4b0b0.pdf
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Summary:The Objectives: safety of blood products is one of the major issues in the area of transfusion medicine. In previous study we found that hepatitis B virus was epidemic in some of Basrah medical institutions to assess the prevalence of anti-HBc and anti-HBs antibodies in serum samples of healthy blood donors negative for both HBsAg and anti-HCV in the Central Blood Bank, Basrah-Iraq. Results: 204 serum samples negative for both HBsAg and anti-HCV collected from healthy blood donors were tested for the presence of HBsAg, anti-HBs, HBeAg, anti-HBe and anti-HBc by using rapid chromatographic immunoassay. Of the 204 samples tested, 13 (6.37%) of the HBsAg negative blood samples were found to be positive for anti-HBc. 3(1.47%) out of 13 anti-HBc positive were found positive for anti-HBs. Conclusion: detection of anti-HBc and anti-HBs antibodies were more important than other markers in detection of latent Hepatitis B virus infection.
ISSN:0253-0759
2413-4414