On the mechanism of gene amplification induced under stress in Escherichia coli.

On the mechanism of gene amplification induced under stress in Escherichia coli.

Gene amplification is a collection of processes whereby a DNA segment is reiterated to multiple copies per genome. It is important in carcinogenesis and resistance to chemotherapeutic agents, and can underlie adaptive evolution via increased expression of an amplified gene, evolution of new gene fun...

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Bibliographic Details
Main Authors: Andrew Slack, P C Thornton, Daniel B Magner, Susan M Rosenberg, P J Hastings
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-04-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1428787?pdf=render

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