THE ROLE OF PULSE REDUCTION THERAPY IN ADDITIONAL IMPROVEMENT OF CLINICAL EFFECTS OF MYOCARDIAL REVASCULARIZATION IN CORONARY HEART DISEASE STABLE ANGINA PATIENTS

The review is focused on the role of ivabradine in percutaneous coronary intervention (PCI) and coronary bypass grafting (CBG) in coronary heart disease patients (CHD) with stable angina. The data provided, on insufficient clinical effect of PCI revascularization with modern medication therapy. Auth...

Full description

Bibliographic Details
Main Authors: D. M. Aronov, M. G. Bubnova
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC  2018-06-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/2823
Description
Summary:The review is focused on the role of ivabradine in percutaneous coronary intervention (PCI) and coronary bypass grafting (CBG) in coronary heart disease patients (CHD) with stable angina. The data provided, on insufficient clinical effect of PCI revascularization with modern medication therapy. Authors argue for improvement of the clinical effect of PCI and CBG by addition of ivabradine together with sufficient (up to maximal) dosages of beta-adrenoblockers (BAB). Inhibition of If-channels of cardiomyocytes with ivabradine makes positive influence on the main clinical endpoints. The role of multiple effect of ivabradine is highlighted, that increase efficacy of the drug.
ISSN:1560-4071
2618-7620