The transcription factor Sp3 regulates the expression of a metastasis-related marker of sarcoma, actin filament-associated protein 1-like 1 (AFAP1L1).

The transcription factor Sp3 regulates the expression of a metastasis-related marker of sarcoma, actin filament-associated protein 1-like 1 (AFAP1L1).

We previously identified actin filament-associated protein 1-like 1 (AFAP1L1) as a metastasis-predicting marker from the gene-expression profiles of 65 spindle cell sarcomas, and demonstrated the up-regulation of AFAP1L1 expression to be an independent risk factor for distant metastasis in multivari...

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Main Authors: Yoichiro Kajita, Tomohisa Kato, Sakura Tamaki, Moritoshi Furu, Ryo Takahashi, Satoshi Nagayama, Tomoki Aoyama, Hiroyuki Nishiyama, Eijiro Nakamura, Toyomasa Katagiri, Yusuke Nakamura, Osamu Ogawa, Junya Toguchida
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3541374?pdf=render

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http://europepmc.org/articles/PMC3541374?pdf=render

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