Green and Facile Assembly of Diverse Fused N-Heterocycles Using Gold-Catalyzed Cascade Reactions in Water

Green and Facile Assembly of Diverse Fused N-Heterocycles Using Gold-Catalyzed Cascade Reactions in Water

The present study describes an AuPPh3Cl/AgSbF6-catalyzed cascade reaction between amine nucleophiles and alkynoic acids in water. This process proceeds in high step economy with water as the sole coproduct, and leads to the generation of two rings, together with the formation of three new bonds in a...

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Bibliographic Details
Main Authors: Xiuwen Jia, Pinyi Li, Xiaoyan Liu, Jiafu Lin, Yiwen Chu, Jinhai Yu, Jiang Wang, Hong Liu, Fei Zhao
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Molecules
Subjects:
amine nucleophiles
alkynoic acids
cascade reaction
gold catalysis
fused N-heterocycles
Online Access:http://www.mdpi.com/1420-3049/24/5/988

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