Silencing of the <it>XAF1 </it>gene by promoter hypermethylation in cancer cells and reactivation to TRAIL-sensitization by IFN-β
<p>Abstract</p> <p>Background</p> <p>XIAP-associated factor 1 (XAF1) is a putative tumor suppressor that exerts its proapoptotic effects through both caspase-dependent and – independent means. Loss of XAF1 expression through promoter methylation has been implicated in t...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2007-03-01
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| Series: | BMC Cancer |
| Online Access: | http://www.biomedcentral.com/1471-2407/7/52 |