Synthesis and Evaluation of the 2-Aminothiazoles as Anti-Tubercular Agents.

Synthesis and Evaluation of the 2-Aminothiazoles as Anti-Tubercular Agents.

The 2-aminothiazole series has anti-bacterial activity against the important global pathogen Mycobacterium tuberculosis. We explored the nature of the activity by designing and synthesizing a large number of analogs and testing these for activity against M. tuberculosis, as well as eukaryotic cells....

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Bibliographic Details
Main Authors: Edward A Kesicki, Mai A Bailey, Yulia Ovechkina, Julie V Early, Torey Alling, Julie Bowman, Edison S Zuniga, Suryakanta Dalai, Naresh Kumar, Thierry Masquelin, Philip A Hipskind, Joshua O Odingo, Tanya Parish
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4865136?pdf=render

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