Pharmacokinetic Analysis of Four Bioactive Iridoid and Secoiridoid Glycoside Components of Radix Gentianae Macrophyllae and Their Synergistic Excretion by HPLC-DAD Combined with Second-Order Calibration

Pharmacokinetic Analysis of Four Bioactive Iridoid and Secoiridoid Glycoside Components of Radix Gentianae Macrophyllae and Their Synergistic Excretion by HPLC-DAD Combined with Second-Order Calibration

Abstract An HPLC-DAD method combined with second-order calibration based on the alternating trilinear decomposition (ATLD) algorithm with the aid of region selection was developed to simultaneously and quantitatively characterize the synergistic relationships and cumulative excretion of the four bio...

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Bibliographic Details
Main Authors: Tian-Ming Yang, Yang-Xi Liu, Hai-Yan Fu, Wei Lan, Han-Bo Su, He-Bin Tang, Qiao-Bo Yin, He-Dong Li, Li-Ping Wang, Hai-Long Wu
Format: Article
Language:English
Published: SpringerOpen 2017-11-01
Series:Natural Products and Bioprospecting
Subjects:
Radix Gentianae Macrophyllae
HPLC-DAD
Second-order calibration
Pharmacokinetic analysis
Online Access:http://link.springer.com/article/10.1007/s13659-017-0145-7

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