A Novel Loss-of-Function Variant in Transmembrane Protein 263 (TMEM263) of Autosomal Dwarfism in Chicken

A Novel Loss-of-Function Variant in Transmembrane Protein 263 (TMEM263) of Autosomal Dwarfism in Chicken

Autosomal dwarfism (adw) in chickens is a growth deficiency caused by a recessive mutation. Characteristic for adw is an approximately 30% growth reduction with short shank. The adw variant was first recognized in the Cornell K-strain of White Leghorns, but the genetic causal variant remained unknow...

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Bibliographic Details
Main Authors: Zhou Wu, Martijn F. L. Derks, Bert Dibbits, Hendrik-Jan Megens, Martien A. M. Groenen, Richard P. M. A. Crooijmans
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Genetics
Subjects:
autosomal dwarfism
body size
recessive trait
chicken
loss-of-function mutation
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00193/full

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