The intercellular synchronization of Ca2+ oscillations evaluates Cx36-dependent coupling.

Connexin36 (Cx36) plays an important role in insulin secretion by controlling the intercellular synchronization of Ca(2+) transients induced during stimulation. The lack of drugs acting on Cx36 channels is a major limitation in further unraveling the molecular mechanism underlying this effect. To sc...

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Bibliographic Details
Main Authors: Sabine Bavamian, Helena Pontes, José Cancela, Anne Charollais, Sergei Startchik, Dimitri Van de Ville, Paolo Meda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3405138?pdf=render

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