TRPV4-Like Non-selective Cation Currents in Cultured Aortic Myocytes

In this study, we provide evidence of critical changes in the expression of non-selective cation currents (NSCC) during culture in rat aortic myocytes. A selective TRPV4 agonist, 4α-phorbol 12,13-didecanoate (4αPDD), had little effect on membrane currents and intracellular Ca2+ (Ca2+i) in freshly is...

Full description

Bibliographic Details
Main Authors: Ryoichi Tanaka, Katsuhiko Muraki, Susumu Ohya, Hisao Yamamura, Noriyuki Hatano, Yuka Itoh, Yuji Imaizumi
Format: Article
Language:English
Published: Elsevier 2008-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319313532