Bet hedging in yeast by heterogeneous, age-correlated expression of a stress protectant.

Genetically identical cells grown in the same culture display striking cell-to-cell heterogeneity in gene expression and other traits. A crucial challenge is to understand how much of this heterogeneity reflects the noise tolerance of a robust system and how much serves a biological function. In bac...

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Bibliographic Details
Main Authors: Sasha F Levy, Naomi Ziv, Mark L Siegal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3348152?pdf=render