Functional characterization of the <it>Saccharomyces cerevisiae </it>protein Chl1 reveals the role of sister chromatid cohesion in the maintenance of spindle length during S-phase arrest

Functional characterization of the <it>Saccharomyces cerevisiae </it>protein Chl1 reveals the role of sister chromatid cohesion in the maintenance of spindle length during S-phase arrest

<p>Abstract</p> <p>Background</p> <p>Metaphase cells have short spindles for efficient bi-orientation of chromosomes. The cohesin proteins hold sister chromatids together, creating Sister Chromatid Cohesion (SCC) that helps in the maintenance of short spindle lengths in...

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Bibliographic Details
Main Authors: Sanyal Kaustuv, Hajra Sujata, Laha Suparna, Das Shankar P, Sinha Pratima
Format: Article
Language:English
Published: BMC 2011-09-01
Series:BMC Genetics
Subjects:
Yeast
Chl1
cohesion
spindle
hydroxyurea
Online Access:http://www.biomedcentral.com/1471-2156/12/83

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