A-to-I editing of Malacoherpesviridae RNAs supports the antiviral role of ADAR1 in mollusks

A-to-I editing of Malacoherpesviridae RNAs supports the antiviral role of ADAR1 in mollusks

Abstract Background Adenosine deaminase enzymes of the ADAR family are conserved in metazoans. They convert adenine into inosine in dsRNAs and thus alter both structural properties and the coding potential of their substrates. Acting on exogenous dsRNAs, ADAR1 exerts a pro- or anti-viral role in ver...

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Bibliographic Details
Main Authors: Umberto Rosani, Chang-Ming Bai, Lorenzo Maso, Maxwell Shapiro, Miriam Abbadi, Stefania Domeneghetti, Chong-Ming Wang, Laura Cendron, Thomas MacCarthy, Paola Venier
Format: Article
Language:English
Published: BMC 2019-07-01
Series:BMC Evolutionary Biology
Subjects:
ADAR
Malacoherpesvirus
OsHV-1
AbHV-1
Mollusks
Oysters
Online Access:http://link.springer.com/article/10.1186/s12862-019-1472-6

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