A multi-target antisense approach against PDE4 and PDE7 reduces smoke-induced lung inflammation in mice

A multi-target antisense approach against PDE4 and PDE7 reduces smoke-induced lung inflammation in mice

<p>Abstract</p> <p>Background</p> <p>Recent development in the field of COPD has focused on strategies aimed at reducing the underlying inflammation through selective inhibition of the phosphodiesterase type IV (PDE4) isoform. Although the anti-inflammatory and bronchod...

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Main Authors: Séguin Rosanne, Séguin Serge, Mouissi Sonia, Moktefi Kamel, Aubé Paméla, Gougeon Jasmine, Higgins Marie-Ève, D'Anjou Hélène, Fortin Marylène, Renzi Paolo M, Paquet Luc, Ferrari Nicolay
Format: Article
Language:English
Published: BMC 2009-05-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/10/1/39

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