CD38 Predicts Favorable Prognosis by Enhancing Immune Infiltration and Antitumor Immunity in the Epithelial Ovarian Cancer Microenvironment

CD38 Predicts Favorable Prognosis by Enhancing Immune Infiltration and Antitumor Immunity in the Epithelial Ovarian Cancer Microenvironment

The identification of predictive biomarkers and novel targets to optimize immunotherapy strategies for epithelial ovarian cancer (EOC) is urgently needed. CD38 is a multifunctional glycoprotein that acts as an ectoenzyme and immune receptor. However, the underlying immunological mechanisms and progn...

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Bibliographic Details
Main Authors: Ying Zhu, Zhigang Zhang, Zhou Jiang, Yang Liu, Jianwei Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Genetics
Subjects:
CD38
ovarian cancer
prognosis
tumor-infiltrating lymphocytes
antitumor immunity
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00369/full

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