Amelogenin Downregulates Interferon Gamma-Induced Major Histocompatibility Complex Class II Expression Through Suppression of Euchromatin Formation in the Class II Transactivator Promoter IV Region in Macrophages

Amelogenin Downregulates Interferon Gamma-Induced Major Histocompatibility Complex Class II Expression Through Suppression of Euchromatin Formation in the Class II Transactivator Promoter IV Region in Macrophages

Enamel matrix derivatives (EMDs)-based periodontal tissue regenerative therapy is known to promote healing with minimal inflammatory response after periodontal surgery, i. e., it promotes wound healing with reduced pain and swelling. It has also been reported that macrophages stimulated with ameloge...

Full description

Bibliographic Details
Main Authors: Karen Yotsumoto, Terukazu Sanui, Urara Tanaka, Hiroaki Yamato, Rehab Alshargabi, Takanori Shinjo, Yuki Nakao, Yukari Watanabe, Chikako Hayashi, Takaharu Taketomi, Takao Fukuda, Fusanori Nishimura
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Immunology
Subjects:
amelogenin
periodontal tissue regeneration
macrophages
major histocompatibility complex class II
interferon gamma
class II transactivator
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00709/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00709/full

Similar Items