Tubular Overexpression of Angiopoietin-1 Attenuates Renal Fibrosis.

Tubular Overexpression of Angiopoietin-1 Attenuates Renal Fibrosis.

Emerging evidence has highlighted the pivotal role of microvasculature injury in the development and progression of renal fibrosis. Angiopoietin-1 (Ang-1) is a secreted vascular growth factor that binds to the endothelial-specific Tie2 receptor. Ang-1/Tie2 signaling is critical for regulating blood...

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Bibliographic Details
Main Authors:	Sudhir Singh, Scott R Manson, Heedoo Lee, Yeawon Kim, Tuoen Liu, Qiusha Guo, Julio J Geminiani, Paul F Austin, Ying Maggie Chen
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2016-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC4959721?pdf=render

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